Release of OMERO & Bio-Formats 5.0.0

The OME team is pleased to announce the full production-ready release of OMERO & Bio-Formats 5.0.0

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Today we are releasing OMERO and Bio-Formats 5.0.0. This is a full, production-ready release of OME’s new software tools. With this release, the 4.4.x line enters maintenance mode and while we will continue to support it throughout 2014, it will only be updated for major bug fixes. We’ve provided scripts to upgrade OMERO 4.4.x installations to 5.0.0.

The 5.0.0 release represents a major change in how the OMERO server handles files at import compared with all previous versions of OMERO. Referred to as ‘OMERO.fs’, this change means that OMERO uses Bio-Formats to read your files directly from the filesystem in their original format, rather than converting them and duplicating the pixel data for storage. Images saved in an OMERO 5.0.0 repository can be accessed by other 3rd party software (this is read-only access). OMERO also now reports on the file integrity at upload so you know if your file is safely stored.

Bio-Formats 5.0.0 includes substantially improved handling of complex multidimensional datasets, including tile-based formats used in digital pathology and support for several new file formats; Aperio AFI, Inveon, MPI-BPC Imspector, Bio-Rad SCN, Yokogawa CellVoyager [1], LaVision Imspector, PCORAW, and Woolz [2].

In addition, 5.0.0 continues our effort to support new multidimensional images. We previously enabled support for FLIM data in OMERO.server, and the FLIMfit application built by the Imperial team. We’ve now added support for FLIM data in OMERO.insight.

The changes in Bio-Formats and OMERO 5.0.0 are especially important for sites working with large multi-GB datasets, e.g., long time lapse, HCS and digital pathology data. With this foundation, we will deliver support for other multidimensional modalities (e.g., light sheet microscopy) later in 2014.

Other features of this release are:

For Bio-Formats:

The software is available from archived downloads.


The software is available from archived downloads.

Upgrade information is available in the server upgrade documentation.

In the near future, the OME team will release updates to several applications, including OMERO.searcher, u-track and several others.

NOTE: Sites that use Java Webstart may see Java security exceptions. Please see this forum post for more information. We are working on obtaining code signing certs and will deliver signed client builds as soon as we can.

Any problems or comments, please use the OME forums or mailing lists.

[1] Thanks to Jean-Yves Tinevez [2] Thanks to Bill Hill

February 25, 2014

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